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學(xué)習(xí)快評丨qibao666888　　非??(fei)編??(bian)碼??(ma)RNA?，尤??(you)其??(qi)是??(shi)長??(chang)鏈??(lian)非??(fei)編??(bian)碼??(ma)RNA在??(zai)哺??(bu)乳??(ru)動??(dong)物??(wu)大??(da)腦??(nao)的??(de)發(fā)??(fa)育??(yu)、成??(cheng)熟??(shu)和??(he)疾??(ji)病??(bing)中??(zhong)發(fā)??(fa)揮?(hui)著??(zhe)重??(zhong)要??(yao)作??(zuo)用??(yong)??。??作?(zuo)為??(wei)此??(ci)次??(ci)的??(de)研??(yan)究??(jiu)亮??(liang)點(diǎn)??(dian)之??(zhi)一??(yi)?，團(tuán)??(tuan)隊(duì)??(dui)首??(shou)次??(ci)整??(zheng)合??(he)了?(le)長??(chang)鏈??(lian)非??(fei)編??(bian)碼??(ma)RNA的??(de)空??(kong)間??(jian)表?(biao)達(dá)?(da)數(shù)??(shu)據(jù)??(ju)?，發(fā)?(fa)現(xiàn)??(xian)長??(chang)鏈?(lian)非??(fei)編??(bian)碼??(ma)RNA的??(de)表??(biao)達(dá)??(da)在?(zai)成??(cheng)年??(nian)小??(xiao)鼠??(shu)大秘(da)腦??(nao)中??(zhong)具??(ju)有??(you)區(qū)??(qu)域??(yu)選??(xuan)擇??(ze)性??(xing)?，在??(zai)發(fā)??(fa)育??(yu)中??(zhong)的??(de)小??(xiao)鼠??(shu)大??(da)腦??(nao)內(nèi)??(nei)則??(ze)呈??(cheng)現(xiàn)??(xian)出??(chu)時(shí)??(shi)空??(kong)動??(dong)態(tài)??(tai)性?(xing)?，為??(wei)神??(shen)經(jīng)??(jing)功??(gong)能??(neng)與??(yu)非??(fei)編??(bian)碼??(ma)RNA相?(xiang)關(guān)??(guan)性??(xing)的??(de)研??(yan)究??(jiu)奠?(dian)定??(ding)了??(le)基??(ji)礎(chǔ)??(chu)??。(完??(wan))　　據(jù)??(ju)介?(jie)紹??(shao)??，哺?(bu)乳??(ru)動??(dong)物??(wu)大??(da)腦??(nao)的??(de)復(fù)??(fu)雜?(za)性??(xing)體??(ti)現(xiàn)??(xian)在??(zai)多??(duo)樣??(yang)的??(de)細(xì)??(xi)胞??(bao)類??(lei)型??(xing)、特??(te)定?(ding)的??(de)空??(kong)間??(jian)分?(fen)布??(bu)??，以??(yi)及秘(ji)復(fù)??(fu)雜?(za)的??(de)神??(shen)經(jīng)??(jing)連??(lian)接??(jie)等?(deng)方??(fang)面??(mian)??。??盡??(jin)管??(guan)科??(ke)學(xué)??(xue)家??(jia)此??(ci)前??(qian)已??(yi)通??(tong)過??(guo)傳??(chuan)統(tǒng)??(tong)細(xì)??(xi)胞??(bao)結(jié)??(jie)構(gòu)??(gou)特??(te)征?(zheng)、單??(dan)細(xì)??(xi)胞??(bao)轉(zhuǎn)??(zhuan)錄??(lu)組??(zu)技?(ji)術(shù)??(shu)??，以??(yi)及??(ji)基??(ji)于??(yu)成??(cheng)像??(xiang)或?(huo)測??(ce)序??(xu)的??(de)空??(kong)間??(jian)組??(zu)學(xué)??(xue)技??(ji)術(shù)??(shu)構(gòu)??(gou)建??(jian)了??(le)多??(duo)種??(zhong)小??(xiao)鼠??(shu)大??(da)腦??(nao)圖??(tu)譜??(pu)??，但??(dan)兼??(jian)具??(ju)單??(dan)細(xì)??(xi)胞??(bao)分??(fen)辨??(bian)率??(lv)和??(he)覆??(fu)蓋??(gai)全??(quan)基??(ji)因??(yin)組??(zu)范??(fan)圍??(wei)的??(de)完??(wan)整??(zheng)大?(da)腦??(nao)圖?(tu)譜??(pu)仍??(reng)屬??(shu)空??(kong)白??(bai)??。本??(ben)次??(ci)鼠??(shu)腦??(nao)圖??(tu)譜??(pu)的??(de)發(fā)??(fa)布??(bu)填??(tian)補(bǔ)??(bu)了??(le)這??(zhe)一??(yi)空??(kong)缺??(que)??，并??(bing)基??(ji)于??(yu)這??(zhe)兩??(liang)個(gè)??(ge)優(yōu)??(you)勢??(shi)取??(qu)得??(de)了??(le)一??(yi)系??(xi)列??(lie)重??(zhong)要??(yao)發(fā)??(fa)現(xiàn)??(xian)??。。