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　　蛋??(dan)白??(bai)質(zhì)??(zhi)是??(shi)由??(you)氨??(an)基?(ji)酸??(suan)序??(xu)列??(lie)構(gòu)??(gou)成??(cheng)的??(de)?，氨??(an)基??(ji)酸??(suan)序??(xu)列??(lie)的??(de)長(zhǎng)??(chang)度??(du)從??(cong)數(shù)??(shu)百??(bai)個(gè)??(ge)到??(dao)上??(shang)千??(qian)個(gè)??(ge)不??(bu)等??(deng)??。??AI時(shí)??(shi)代??(dai)?，數(shù)??(shu)據(jù)??(ju)是??(shi)推??(tui)動(dòng)??(dong)技??(ji)術(shù)??(shu)進(jìn)??(jin)步??(bu)的??(de)核??(he)心??(xin)資??(zi)源??(yuan)?，龐??(pang)大??(da)的?(de)蛋??(dan)白??(bai)質(zhì)??(zhi)序??(xu)列??(lie)數(shù)?(shu)據(jù)??(ju)集??(ji)能??(neng)幫??(bang)助??(zhu)模??(mo)型??(xing)更??(geng)好??(hao)地??(di)理?(li)解??(jie)蛋??(dan)白??(bai)質(zhì)??(zhi)的??(de)序??(xu)列??(lie)、結(jié)??(jie)構(gòu)??(gou)和??(he)功??(gong)能??(neng)關(guān)??(guan)系??(xi)??。洪??(hong)亮??(liang)團(tuán)??(tuan)隊(duì)??(dui)建??(jian)立??(li)的?(de)蛋??(dan)白??(bai)質(zhì)?(zhi)序??(xu)列??(lie)數(shù)??(shu)據(jù)??(ju)集?(ji)Venus-Pod(Venus-Protein Outsize Dataset)含?(han)有??(you)近??(jin)90億?(yi)條??(tiao)蛋??(dan)白??(bai)質(zhì)??(zhi)序??(xu)列?(lie)?，包??(bao)含?(han)數(shù)??(shu)億??(yi)個(gè)??(ge)功??(gong)能??(neng)標(biāo)??(biao)簽??(qian)?，是??(shi)全??(quan)球??(qiu)數(shù)??(shu)據(jù)??(ju)規(guī)??(gui)模??(mo)最??(zui)大??(da)、功??(gong)能??(neng)批??(pi)注??(zhu)標(biāo)?(biao)簽??(qian)最??(zui)多??(duo)的?(de)數(shù)?(shu)據(jù)??(ju)集??(ji)?，也??(ye)是??(shi)另??(ling)一??(yi)行??(xing)業(yè)??(ye)知??(zhi)名??(ming)模??(mo)型??(xing)——美??(mei)國(guó)??(guo)ESM-C模??(mo)型??(xing)訓(xùn)??(xun)練??(lian)用??(yong)的?(de)21億??(yi)蛋??(dan)白??(bai)質(zhì)??(zhi)序??(xu)列?(lie)的??(de)4倍??(bei)體??(ti)量??(liang)???！　　拔??(wo)們?(men)訓(xùn)?(xun)練??(lian)了??(le)Venus(啟??(qi)明??(ming)星??(xing))系?(xi)列??(lie)模??(mo)型??(xing)??，與??(yu)DeepMind團(tuán)??(tuan)隊(duì)??(dui)的??(de)AlphaFold預(yù)??(yu)測(cè)?(ce)蛋??(dan)白??(bai)質(zhì)??(zhi)結(jié)??(jie)構(gòu)??(gou)不?(bu)同??(tong)??，這?(zhe)個(gè)??(ge)模??(mo)型??(xing)學(xué)??(xue)習(xí)??(xi)自??(zi)然??(ran)界??(jie)蛋??(dan)白??(bai)質(zhì)??(zhi)序??(xu)列??(lie)的??(de)組??(zu)織??(zhi)規(guī)??(gui)則??(ze)以??(yi)及??(ji)它?(ta)與??(yu)功??(gong)能??(neng)之??(zhi)間??(jian)的??(de)關(guān)??(guan)系??(xi)??，其??(qi)預(yù)??(yu)測(cè)??(ce)蛋??(dan)白??(bai)質(zhì)??(zhi)突??(tu)變??(bian)功??(gong)能??(neng)的??(de)精??(jing)度??(du)位??(wei)居??(ju)行??(xing)業(yè)??(ye)榜??(bang)單??(dan)之??(zhi)首??(shou)??。??”洪??(hong)亮?(liang)說(shuō)??(shuo)??，Venus系??(xi)列??(lie)模??(mo)型??(xing)具??(ju)備??(bei)兩??(liang)大??(da)核??(he)心?(xin)功??(gong)能??(neng)：“AI定??(ding)向??(xiang)進(jìn)??(jin)化??(hua)”與?(yu)“AI挖?(wa)酶??(mei)”??。這??(zhe)些??(xie)超??(chao)常??(chang)規(guī)??(gui)功??(gong)能?(neng)的??(de)蛋??(dan)白??(bai)質(zhì)?(zhi)在??(zai)生??(sheng)物??(wu)技??(ji)術(shù)??(shu)、醫(yī)??(yi)藥??(yao)研??(yan)發(fā)??(fa)和??(he)工??(gong)業(yè)??(ye)生??(sheng)產(chǎn)??(chan)中??(zhong)具?(ju)有??(you)巨??(ju)大??(da)的??(de)應(yīng)??(ying)用??(yong)潛??(qian)力??(li)??，能??(neng)夠??(gou)為??(wei)相??(xiang)關(guān)?(guan)領(lǐng)??(ling)域??(yu)帶??(dai)來(lái)??(lai)創(chuàng)??(chuang)新?(xin)和??(he)突??(tu)破??(po)??。。